全部产品分类
品牌 |
Leading Biology | 货号 |
APR02367G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IER3 / IEX-1 Antibody (Internal).
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分子量 |
17kDa
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type II membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
a 24 amino acid peptide near the center of human IEX1
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通用名 |
DIF2, IEX1, PRG1
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基因ID |
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UniProt ID |
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功能 |
May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A- PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
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总结 |
May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A- PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P
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稀释方法 |
IHC-P (5 μg/ml), WB (2-4 μg/ml),
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图像 |
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说明书 |
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数量 |
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