全部产品分类
品牌 |
Leading Biology | 货号 |
APR02266G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FEM1B Antibody (aa609-622).
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分子量 |
70kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment. Associated with chromatin
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Dog
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靶点 |
Peptide (DINYQDQIPRTLEE) corresponding to amino acids 609 to 622 of human F1Aa This sequence is identical to the corresponding sequence of mouse FEM1b.
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通用名 |
F1AA, KIAA0396
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基因ID |
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UniProt ID |
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功能 |
Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
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总结 |
Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF
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稀释方法 |
IHC-P (10 μg/ml), WB (0.5-1 μg/ml),
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图像 |
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说明书 |
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数量 |
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