品牌 |
Leading Biology | 货号 |
APR02258G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RYBP Antibody (aa215-228).
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分子量 |
25kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Nucleus, nucleoplasm. Note=Primarily found in the nucleus. Detected in a punctate pattern likely to represent Polycomb group (PcG) bodies (By similarity).
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Horse, Bovine, Dog
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靶点 |
synthetic peptide (TPKGDMSAVNDESF) corresponding to amino acids 215 to 228 of human DEDAF The sequence is identical to that of mouse origin
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通用名 |
DEDAF, YEAF1
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基因ID |
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UniProt ID |
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功能 |
Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis.
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总结 |
Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF
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稀释方法 |
IHC-P (2.5 μg/ml), WB (0.5-1 μg/ml),
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图像 |
Immunofluorescence of DEDAF in A549 cells with DEDAF antibody at 20 ug/ml.
Western blot of DEDAF expression in human A549 (lane A), HepG2 (lane B), and mouse 3T3 (lane C)...
Anti-RYBP antibody IHC of human placenta. |
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说明书 |
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数量 |
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