全部产品分类
品牌 |
Leading Biology | 货号 |
APR02243G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CARMA1 / CARD11 Antibody (C-Terminus).
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分子量 |
133kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Membrane raft. Note=Colocalized with DPP4 in membrane rafts
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
synthetic peptide corresponding to amino acids at the C-terminus of human CARMA1
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通用名 |
CARMA1
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基因ID |
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UniProt ID |
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功能 |
Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
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总结 |
Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF
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稀释方法 |
IHC-P (5 μg/ml), WB (0.5-2 μg/ml),
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图像 |
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说明书 |
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数量 |
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