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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > fibrinogen beta chain (aa177-190) Antibody (internal region)

fibrinogen beta chain (aa177-190) Antibody (internal region)

货号 货期 规格 / 价格 询价
APG00932G 0.1mg / ¥4950

fibrinogen beta chain (aa177-190) Antibody (internal region)

品牌

Leading Biology

货号

APG00932G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality fibrinogen beta chain (aa177-190) Antibody (internal region).

分子量

55928 Da

细胞定位

Antigen Cellular Localization: Secreted.

宿主

Goat

种属反应性

Human

亚型

IgG

基因ID

UniProt ID

功能

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

总结

This antibody is expected to recognize both reported isoforms (NP_005132.2; NP_001171670.1).

形式

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

图像

APG00932G (0.01 μg/ml) staining of Human Liver lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

说明书

数量

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