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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Trp63 (mouse) Antibody (C or N-Term)

Trp63 (mouse) Antibody (C or N-Term)

货号 货期 规格 / 价格 询价
APG00814G 0.1mg / ¥4950

Trp63 (mouse) Antibody (C or N-Term)

品牌

Leading Biology

货号

APG00814G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Trp63 (mouse) Antibody (C or N-Term).

分子量

76785 Da

细胞定位

Antigen Cellular Localization: Nucleus

宿主

Goat

种属反应性

Human

亚型

IgG

通用名

KET, P63, P73H, P73L, TP73L

基因ID

UniProt ID

功能

Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.

总结

This antibody is expected to recognize reported isoforms d, e, f, g, h. (NP_035771.1; NP_001120736.1; NP_001120734.1; NP_001120735.1; NP_001120737.1).

形式

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

图像

APG00814G (0.3 μg/ml) staining of A431 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

说明书

数量

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