品牌 |
Leading Biology | 货号 |
APG00807G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RRAD (aa36-48) Antibody (internal region).
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分子量 |
33245 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane.
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宿主 |
Goat
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种属反应性 |
Mouse
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亚型 |
IgG
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通用名 |
RAD
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基因ID |
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UniProt ID |
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功能 |
May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
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总结 |
Reported variants represent identical protein: NP_004156.1, NP_001122322.1
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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图像 |
A): APG00807G (0.5 μg/ml) staining of HEK293 lysates overexpressing several HA-tagged Mouse GTPases, including Rrad (10 μg protein in RIPA buffer) and compared with an HA-specific antibody. B): APG00807G (0.5 μg/ml) staining of WT and KO lysates of Mouse Heart (100 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Data provided by Prof. D Andres, University of Kentucky College of Medicine, USA. |
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说明书 |
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数量 |
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