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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-UEV2V2 / MMS2 Antibody

Goat Anti-UEV2V2 / MMS2 Antibody

货号 货期 规格 / 价格 询价
APG00357G 0.1mg / ¥4950

Goat Anti-UEV2V2 / MMS2 Antibody

品牌

Leading Biology

货号

APG00357G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-UEV2V2 / MMS2 Antibody.

分子量

16363 Da

宿主

Goat

种属反应性

Human

亚型

IgG

通用名

MMS2, UEV2

基因ID

UniProt ID

功能

Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

总结

Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes.

形式

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

图像

APG00357G staining (0.5 μg/ml) of human brain lysate (RIPA buffer, 30 μg total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.

说明书

数量

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