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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-NRAS Antibody

Goat Anti-NRAS Antibody

货号 货期 规格 / 价格 询价
APG00222G 0.1mg / ¥4950

Goat Anti-NRAS Antibody

品牌

Leading Biology

货号

APG00222G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-NRAS Antibody.

分子量

21229 Da

细胞定位

Antigen Cellular Localization: Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor. Note=Shuttles between the plasma membrane and the Golgi apparatus

宿主

Goat

种属反应性

Human, Rat

亚型

IgG

通用名

HRAS1

基因ID

UniProt ID

功能

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

总结

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML).

形式

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC, E

图像

HEK293 overexpressing NRAS (RC202681) and probed with APG00222G (mock transfection in first lane), tested by Origene.

APG00222G (2.5 μg/ml) staining of paraffin embedded Human Small Intestine. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

APG00222G (0.01 μg/ml) staining of A431 lysate (35 μg protein in RIPA buffer).Primary incubation was 1 hour.Detected by chemiluminescence.

说明书

数量

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