品牌 |
Leading Biology | 货号 |
APG00152G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-GRAP2 / GRID / Grf40 Antibody.
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分子量 |
37909 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Endosome
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宿主 |
Goat
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种属反应性 |
Human
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亚型 |
IgG
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通用名 |
GADS, GRB2L, GRID
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基因ID |
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UniProt ID |
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功能 |
Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
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总结 |
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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图像 |
HEK293 overexpressing GRAP2 (RC206546) and probed with APG00152G (mock transfection in first lane), tested by Origene.
APG00152G staining (0.5 μg/ml) of Jurkat lysate (RIPA buffer, 30 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. |
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说明书 |
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数量 |
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