全部产品分类
品牌 |
Leading Biology | 货号 |
APR00126G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MMP-17 Antibody.
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分子量 |
66653 Da
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细胞定位 |
Antigen Cellular Localization:
Isoform Long: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
MMP17
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亚型 |
Rabbit IgG
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通用名 |
MT4MMP
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基因ID |
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UniProt ID |
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功能 |
Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
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总结 |
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. MMP-17 (also designated MT-MMP4 or MT4-MMP) is a glycosylphosphatidylinositol (GPI)-anchored proteinase and is mainly expressed in the brain, leukocytes, colon, ovary and testis.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, IP
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说明书 |
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数量 |
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