全部产品分类
品牌 |
Leading Biology | 货号 |
APR00096G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Bcl-3 Antibody.
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分子量 |
47584 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Ubiquitination via 'Lys- 63'-linked ubiquitin chains is required for nuclear accumulation
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Bcl-3
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亚型 |
Rabbit IgG
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通用名 |
BCL4, D19S37
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基因ID |
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UniProt ID |
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功能 |
Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity).
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总结 |
Bcl-3, a proto-oncogene, is believed to be involved in certain human B cell leukemias. It encodes a protein that functions as an IkB-like molecule for native NFkB, but is specific for the p50 subunit of NFkB.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, IP
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说明书 |
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数量 |
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