全部产品分类
品牌 |
Leading Biology | 货号 |
APR00003G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Caspase-11 Antibody.
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分子量 |
42742 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane. Mitochondrion
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宿主 |
Rabbit
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种属反应性 |
Mouse, Rat
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靶点 |
Caspase-11
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亚型 |
Rabbit IgG
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通用名 |
Casp11, Caspl, Ich3
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基因ID |
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UniProt ID |
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功能 |
Involved in ER-stress induced apoptosis. Cleaves caspase-1 (By similarity). Involved in the activation cascade of caspases responsible for apoptosis execution. Promotes IL-1 beta processing by ICE, so may also have a role in inflammatory responses.
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总结 |
Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-11 is also synthesized as inactive pro-enzyme that are processed in cells undergoing apoptosis or inflammation. The processed form of caspase-11 consists of large and small subunits which associate to form an active enzyme.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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图像 |
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说明书 |
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数量 |
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