品牌 |
Leading Biology | 货号 |
APR00712G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MKL1 antibody - C-terminal region.
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分子量 |
106kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Binding to globular actin is required to maintain cytoplasmic localization. Nuclear localization is regulated by MICAL2, which mediates depolymerization of nuclear globular actin, promoting retention of MKL1 in the nucleus and subsequent formation of an active complex with SRF (By similarity).
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog
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通用名 |
Bsac
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基因ID |
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UniProt ID |
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功能 |
Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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图像 |
WB Suggested Anti-MKL1 Antibody Titration: 1.25μg/ml ELISA Titer: 1:1562500 Positive Control: NIH/3T3 cell lysate |
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说明书 |
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数量 |
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