全部产品分类
品牌 |
Leading Biology | 货号 |
APR00294G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality sRANK Ligand Polyclonal Antibody.
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分子量 |
35003 Da
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细胞定位 |
Antigen Cellular Localization:
Isoform 1: Cell membrane; Single-pass type II membrane protein Isoform 3: Cytoplasm.
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宿主 |
Rabbit
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种属反应性 |
Mouse
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靶点 |
RANKL
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亚型 |
Rabbit IgG
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通用名 |
Opgl, Rankl, Trance
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基因ID |
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UniProt ID |
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功能 |
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
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总结 |
RANK (receptor activator of NF-kB) is a member of the TNFR family, identified as a dendritic cell membrane protein. Murine sRANK Ligand is a soluble 19.4 kDa protein, comprising the TNF-like extracellular domain of RANKL (174 amino acids). The full length of RANK Ligand is 39.6 kDa containing 36 amino acids.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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说明书 |
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数量 |
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