全部产品分类
品牌 |
Leading Biology | 货号 |
APR00233G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Perilipin A Antibody.
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分子量 |
55596 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum. Lipid droplet. Note=Lipid droplet surface- associated
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Perilipin A
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亚型 |
Rabbit IgG
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通用名 |
Peri, Plin
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基因ID |
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UniProt ID |
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功能 |
Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone- sensitive lipase (HSL). Its absence may result in leanness (By similarity). Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.
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总结 |
Perilipin is a protein produced and secreted by adipose cells. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory effects on hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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图像 |
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说明书 |
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数量 |
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