品牌 |
Leading Biology | 货号 |
APR00208G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GPVI Antibody.
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分子量 |
36866 Da
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细胞定位 |
Antigen Cellular Localization:
Isoform 1: Cell membrane; Single-pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
GPV
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亚型 |
Rabbit IgG
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基因ID |
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UniProt ID |
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功能 |
Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2.
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总结 |
Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets. GPVI plays an important role in platelet procoagulant activity and the formation of thrombin and fibrin.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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图像 |
Western blot analysis of GPVI expression in Jurkat cell lysate (Lane 1, 2). |
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说明书 |
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数量 |
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