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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Dio-1 Antibody

Dio-1 Antibody

货号 货期 规格 / 价格 询价
APR00143G 100 μg / ¥4950

Dio-1 Antibody

品牌

Leading Biology

货号

APR00143G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Dio-1 Antibody.

分子量

247176 Da

细胞定位

Antigen Cellular Localization: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Translocates to the mitotic spindle upon loss of interaction with H3K4me3 during early mitosis (By similarity). Translocates to the nucleus after pro-apoptotic stimuli.

宿主

Rabbit

种属反应性

Human, Mouse

靶点

Dio-1

亚型

Rabbit IgG

通用名

Datf1, Dio1

基因ID

UniProt ID

功能

Required for early embryonic stem cell development (By similarity). Putative transcription factor, weakly pro-apoptotic when overexpressed.

总结

Apoptosis plays an important role in many cellular processes. Dio-1 (Death Inducer-O bliterator-1), a putative transcription factor, has been indicated to function in the onset of apoptosis. Dio-1 expression is upregulated when an apoptosis is detected. It translocates to the nucleus, and activates apoptosis during limb development. Dio-1 expression can be suppressed by caspase inhibitors and Bcl-2 expression.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB

说明书

数量

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