品牌 |
Leading Biology | 货号 |
APR00005G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BAK1 Antibody.
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分子量 |
23409 Da
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细胞定位 |
Antigen Cellular Localization:
Mitochondrion membrane; Single-pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
Bak1
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亚型 |
Rabbit IgG
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通用名 |
BAK, BCL2L7, CDN1
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基因ID |
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UniProt ID |
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功能 |
In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
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总结 |
Bak is a homolog of apoptosis inhibitor Bcl-2. Bak is a member of the Bcl-2 family of proteins and contains Bcl-2 homology region (BH-) 1, 2 and 3. Unlike Bcl-2, Bak promotes cell death and counteracts the anti-apoptotic effect of Bcl-2. The immunoaffinity purified antibody detects a 30 kDa band, corresponding to the expected molecular weight of Bak on SDS-PAGE immunoblots.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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图像 |
Western blot analysis of BAK1 using Jurkat cell lysate (Lane 1 & 2). |
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说明书 |
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数量 |
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