全部产品分类
品牌 |
Leading Biology | 货号 |
APR05755G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL1RN Antibody (C-term).
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分子量 |
20055 Da
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细胞定位 |
Antigen Cellular Localization:
Isoform 1: Secreted. Isoform 3: Cytoplasm.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
147-177 aa
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靶点 |
This IL1RN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-177 amino acids from the C-terminal region of human IL1RN.
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亚型 |
Rabbit Ig
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通用名 |
IL1F3, IL1RA
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基因ID |
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UniProt ID |
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功能 |
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
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总结 |
The protein is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of its gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, FC, IF, E
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稀释方法 |
WB~~1:1000
FC~~1:10~50
IF~~1:10~50
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图像 |
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说明书 |
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数量 |
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