全部产品分类
品牌 |
Leading Biology | 货号 |
APR05738G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GRB2 Antibody (Y209).
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分子量 |
25206 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Endosome. Golgi apparatus
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
187-216 aa
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靶点 |
This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from human GRB2.
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亚型 |
Rabbit Ig
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通用名 |
ASH
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基因ID |
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UniProt ID |
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功能 |
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
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总结 |
GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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图像 |
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说明书 |
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数量 |
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