全部产品分类
品牌 |
Leading Biology | 货号 |
APR05642G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HMGA2 Antibody (C-term).
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分子量 |
11832 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
64-92 aa
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靶点 |
This HMGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human HMGA2.
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亚型 |
Rabbit Ig
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通用名 |
HMGIC
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基因ID |
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UniProt ID |
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功能 |
Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes.
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总结 |
This gene encodes a protein that belongs to thenon-histone chromosomal high mobility group (HMG) protein family.HMG proteins function as architectural factors and are essentialcomponents of the enhancesome. This protein contains structuralDNA-binding domains and may act as a transcriptional regulatingfactor. Identification of the deletion, amplification, andrearrangement of this gene that are associated with myxoidliposarcoma suggests a role in adipogenesis and mesenchymaldifferentiation. A gene knock out study of the mouse counterpartdemonstrated that this gene is involved in diet-induced obesity.Alternate transcriptional splice variants, encoding differentisoforms, have been characterized.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, FC, E
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稀释方法 |
WB~~1:1000
FC~~1:10~50
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图像 |
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说明书 |
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数量 |
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