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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > ACTA1/alpha-actin Antibody (C-term)

ACTA1/alpha-actin Antibody (C-term)

货号 货期 规格 / 价格 询价
APR04217G 100 μl / ¥4950

ACTA1/alpha-actin Antibody (C-term)

品牌

Leading Biology

货号

APR04217G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACTA1/alpha-actin Antibody (C-term).

分子量

42051 Da

细胞定位

Antigen Cellular Localization: Cytoplasm, cytoskeleton.

宿主

Rabbit

种属反应性

Human, Rat

免疫原

189-217 aa

靶点

This ACTA1/Alpha-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the C-terminal region of human ACTA1/Alpha-actin.

亚型

Rabbit Ig

通用名

ACTA

基因ID

UniProt ID

功能

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

总结

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

IHC-P, WB, E

稀释方法

IHC-P~~1:25 WB~~1:1000

图像

APR04217G staining ACTA1/alpha-actin in human heart tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.

ACTA1/α-actin Antibody (C-term) (Cat. APR04217G) western blot analysis in human normal uterus and placenta,rat heart tissue lysates (35ug/lane).This demonstrates the ACTA1/α-actin antibody detected the ACTA1/α-actin protein (arrow).

说明书

数量

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