品牌 |
Leading Biology | 货号 |
APR03968G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PRDM1 Antibody (N-term).
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分子量 |
91771 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus {ECO:0000250|UniProtKB:Q60636}. Cytoplasm
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
106-134 aa
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靶点 |
This PRDM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the N-terminal region of human PRDM1.
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亚型 |
Rabbit Ig
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通用名 |
BLIMP1
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基因ID |
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UniProt ID |
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功能 |
Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569).
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总结 |
This gene encodes a protein that acts as a repressor ofbeta-interferon gene expression. The protein binds specifically tothe PRDI (positive regulatory domain I element) of the beta-IFNgene promoter. Transcription of this gene increases upon virusinduction. Two alternatively spliced transcript variants thatencode different isoforms have been reported.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
PRDM1 Antibody (N-term) (Cat. APR03968G) western blot analysis in HL-60 cell line and mouse spleen tissue lysates (35ug/lane).This demonstrates the PRDM1 antibody detected the PRDM1 protein (arrow). |
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说明书 |
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数量 |
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