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MMP3 Antibody (N-term)

APR03830G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
APR03830G		100 μl / ￥4950

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MMP3 Antibody (N-term)

品牌	Leading Biology	货号	APR03830G
产品分类	Polyclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MMP3 Antibody (N-term).
分子量	53977 Da
细胞定位	Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix
宿主	Rabbit
种属反应性	Human
免疫原	30-59 aa
靶点	This MMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human MMP3.
亚型	Rabbit Ig
通用名	STMY1
基因ID	4314
UniProt ID	P08254
功能	Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
总结	Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. This gene encodes an enzyme whichdegrades fibronectin, laminin, collagens III, IV, IX, and X, andcartilage proteoglycans. The enzyme is thought to be involved inwound repair, progression of atherosclerosis, and tumor initiation.The gene is part of a cluster of MMP genes which localize tochromosome 11q22.3.
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, IHC-P, IF, E
稀释方法	WB~~1:1000 IHC-P~~1:10~50 IF~~1:10~50
图像	Western blot analysis of lysates from HepG2,NCI-H460,Raji,Ramos cell line (from left to right),using MMP3 Antibody (N-term)(Cat. APR03830G).APR03830G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane. MMP3 Antibody (N-term) (Cat. APR03830G)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. MMP3 Antibody (N-term) (Cat. APR03830G)immunohistochemistry analysis in formalin fixed and paraffin embedded human esophagus carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
说明书	Product Datasheet Protocol
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