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SUPV3L1 Antibody (N-term)

APR06194G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
APR06194G		100 μl / ￥4950

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SUPV3L1 Antibody (N-term)

品牌	Leading Biology	货号	APR06194G
产品分类	Polyclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SUPV3L1 Antibody (N-term).
分子量	87991 Da
细胞定位	Antigen Cellular Localization: Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid
宿主	Rabbit
种属反应性	Human, Mouse, Rat
免疫原	93-121 aa
靶点	This SUPV3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-121 amino acids from the N-terminal region of human SUPV3L1.
亚型	Rabbit Ig
通用名	SUV3
基因ID	6832
UniProt ID	Q8IYB8
功能	Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
总结	SUV3L1 is an ATPase and DNA/RNA helicase able to unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes in the 5'-3' direction. It may protect cells from apoptosis.
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, IHC-P, FC, E
稀释方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
图像	Western blot analysis of lysates from SW620, PC-3 cell line, mouse kidney, rat kidney tissue lysate (from left to right), using SUPV3L1 Antibody (N-term)(APR06194G). APR06194G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane. Western blot analysis of SUPV3L1 Antibody (N-term) (Cat. APR06194G) in K562 cell line lysates (35ug/lane). SUPV3L1 (arrow) was detected using the purified Pab. SUPV3L1 Antibody (N-term) (Cat. APR06194G) IHC analysis in formalin fixed and paraffin embedded prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SUPV3L1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
说明书	Product Datasheet Protocol
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