品牌 |
Leading Biology | 货号 |
APR06190G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PRUNE Antibody (C-term).
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分子量 |
50200 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Cell junction, focal adhesion. Note=In some transfected cells a nuclear staining is also observed
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
360-389 aa
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靶点 |
This PRUNE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-389 amino acids from the C-terminal region of human PRUNE.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.
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总结 |
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. It plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, FC, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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图像 |
Western blot analysis of PRUNE Antibody (C-term) (Cat. APR06190G) in Jurkat cell line lysates (35ug/lane). PRUNE (arrow) was detected using the purified Pab.
PRUNE Antibody (C-term) (Cat. APR06190G) IHC analysis in formalin fixed and paraffin embedded prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PRUNE Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
PRUNE Antibody (C-term) (Cat. APR06190G) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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说明书 |
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数量 |
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