全部产品分类
品牌 |
Leading Biology | 货号 |
APR06185G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality INSC Antibody (Center).
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分子量 |
63469 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Note=Localizes to the apical cortex of mitotic epidermal cells and to the apical side of neuronal progenitor cells.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
410-437 aa
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靶点 |
This INSC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-437 amino acids from the Central region of human INSC.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium.
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总结 |
In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
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图像 |
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说明书 |
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数量 |
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