品牌 |
Leading Biology | 货号 |
APR06182G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BCL11A Antibody (C-term).
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分子量 |
91197 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles (By similarity).
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
806-835 aa
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靶点 |
This BCL11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 806-835 amino acids from the C-terminal region of human BCL11A.
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亚型 |
Rabbit Ig
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通用名 |
CTIP1, EVI9, KIAA1809, ZNF856
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基因ID |
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UniProt ID |
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功能 |
Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity).
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总结 |
BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
Western blot analysis of BCL11A Antibody (C-term) (Cat. APR06182G) in Jurkat, Ramos, 293, NCI-H460 cell line lysates (35ug/lane). BCL11A (arrow) was detected using the purified Pab. |
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说明书 |
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数量 |
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