品牌 |
Leading Biology | 货号 |
APR06011G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CTGF Antibody (C-term).
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分子量 |
38091 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix. Secreted
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
315-349 aa
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靶点 |
This CTGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-349 amino acids from the C-terminal region of human CTGF.
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亚型 |
Rabbit Ig
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通用名 |
CCN2, HCS24, IGFBP8
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基因ID |
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UniProt ID |
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功能 |
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
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总结 |
Connective tissue growth factor (CTGF), a member of the CCN family of secreted matricellular proteins, regulates fibrosis, angiogenesis, cell proliferation, apoptosis, tumor growth, and metastasis.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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图像 |
All lanes : Anti-CTGF Antibody (C-term) at 1:1000 dilution Lane 1: A549 whole cell lysate Lane 2: NCI-H460 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 38 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CTGF antibody (C-term) (Cat.APR06011G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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说明书 |
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数量 |
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