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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > HSPA1A/HSPA1B Antibody (Y41)

HSPA1A/HSPA1B Antibody (Y41)

货号 货期 规格 / 价格 询价
APR05936G 100 μl / ¥4950

HSPA1A/HSPA1B Antibody (Y41)

品牌

Leading Biology

货号

APR05936G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HSPA1A/HSPA1B Antibody (Y41).

分子量

70052 Da

细胞定位

Antigen Cellular Localization: Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs

宿主

Rabbit

种属反应性

Human

免疫原

19-48 aa

靶点

This HSPA1A/HSPA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from human HSPA1A/HSPA1B.

亚型

Rabbit Ig

通用名

HSPA1, HSX70

基因ID

UniProt ID

功能

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.

总结

HSPA1A is a member of the heat shock protein 70 family. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

图像

Western blot analysis of HSPA1A (arrow) using rabbit polyclonal HSPA1A Antibody (S41) (Cat.APR05936G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HSPA1A gene (Lane 2) (Origene Technologies).

说明书

数量

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