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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > NEK8 Antibody (C-term)

NEK8 Antibody (C-term)

货号 货期 规格 / 价格 询价
APR05843G 100 μl / ¥4950

NEK8 Antibody (C-term)

品牌

Leading Biology

货号

APR05843G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NEK8 Antibody (C-term).

分子量

74806 Da

细胞定位

Antigen Cellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, cilium Note=Predominantly cytoplasmic. Localizes to the proximal region of the primary cilium and is not observed in dividing cells

宿主

Rabbit

种属反应性

Human

免疫原

573-604 aa

靶点

This NEK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-604 amino acids from the C-terminal region of human NEK8.

亚型

Rabbit Ig

通用名

JCK, NEK12A

基因ID

UniProt ID

功能

Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through targeting of proteins to the cilia (By similarity). Plays a role in organogenesis and is involved in the regulation of the Hippo signaling pathway.

总结

NEK8 is a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystickidney disease in humans.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

图像

The anti-NEK8 Pab (Cat. APR05843G) is used in Western blot to detect NEK8 in A2058 cell lysate.

说明书

数量

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