全部产品分类
品牌 |
Leading Biology | 货号 |
APR05718G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MMP7 Antibody (Center).
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分子量 |
29677 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
117-146 aa
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靶点 |
This MMP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-146 amino acids from the Central region of human MMP7.
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亚型 |
Rabbit Ig
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通用名 |
MPSL1, PUMP1
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基因ID |
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UniProt ID |
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功能 |
Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
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总结 |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP7 degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
IF~~1:10~50
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图像 |
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说明书 |
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数量 |
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