品牌 |
Leading Biology | 货号 |
APR05706G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MAGEH1 Antibody (C-term).
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分子量 |
24441 Da
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
186-218 aa
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靶点 |
This MAGEH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-218 amino acids from the C-terminal region of human MAGEH1.
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亚型 |
Rabbit Ig
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通用名 |
1-Apr
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基因ID |
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UniProt ID |
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总结 |
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGEH1 is not fully elucidated, it may play a role in embryonal development and tumor transformation or aspects of tumor progression.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
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图像 |
The anti-MAGEH1 Pab (Cat. APR05706G) is used in Western blot to detect MAGEH1 in Jurkat cell lysate.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Western blot analysis of MAGEH1 (arrow) using rabbit polyclonal MAGEH1 Antibody (D201) (Cat. APR05706G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MAGEH1 gene. |
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说明书 |
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数量 |
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