全部产品分类
品牌 |
Leading Biology | 货号 |
APR05358G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality C19orf21 Antibody (N-term).
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分子量 |
75357 Da
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细胞定位 |
Antigen Cellular Localization:
Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Predominantly localizes to cortical actin structures during interphase and mitosis Present in retraction fibers, which are formed at former adhesion sites during mitosis, and at spicular membrane protrusions in re- attaching cytokinetic cells. Partially colocalizes with cytoplasmic F-actin. Not detected at microtubules at interphase, nor at spindle during mitosis
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
63-91 aa
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靶点 |
This C19orf21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the N-terminal region of human C19orf21.
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亚型 |
Rabbit Ig
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通用名 |
C19orf21
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基因ID |
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UniProt ID |
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功能 |
Plays a role in mitotic spindle orientation and mitotic progression. Regulates the distribution of dynactin at the cell cortex in a PLK1-dependent manner, thus stabilizing cortical and astral microtubule attachments required for proper mitotic spindle positioning. May link microtubules to the actin cytospkeleton and focal adhesions. May be required for directed cell migration and centrosome orientation. May also be necessary for proper stacking of the Golgi apparatus.
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总结 |
The exact function of C19orf21 remains unknown.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, FC, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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图像 |
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说明书 |
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数量 |
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