全部产品分类
品牌 |
Leading Biology | 货号 |
APR05172G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-MYC(T58) Antibody.
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分子量 |
48804 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus, nucleoplasm. Nucleus, nucleolus
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.
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亚型 |
Rabbit Ig
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通用名 |
BHLHE39
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基因ID |
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UniProt ID |
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功能 |
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.
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总结 |
MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
DB, WB, E
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稀释方法 |
DB~~1:500
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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