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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > NYREN18 Antibody (N-term)

NYREN18 Antibody (N-term)

货号 货期 规格 / 价格 询价
APR05044G 100 μl / ¥4950

NYREN18 Antibody (N-term)

品牌

Leading Biology

货号

APR05044G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NYREN18 Antibody (N-term).

分子量

70538 Da

细胞定位

Antigen Cellular Localization: Nucleus. Note=Predominantly nuclear

宿主

Rabbit

种属反应性

Human, Mouse

免疫原

87-117 aa

靶点

This NYREN18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-117 amino acids from the N-terminal region of human NYREN18.

亚型

Rabbit Ig

通用名

NYREN18

基因ID

UniProt ID

功能

Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.

总结

NYREN18 is a specific down-regulator of the NEDD8 conjugation system. It recruits NEDD8 and its conjugates to the proteasome for degradation. It also interacts with PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

稀释方法

WB~~1:1000 IHC-P~~1:50~100

图像

The anti-NYREN18 N-term Pab (Cat. APR05044G) is used in Western blot to detect NYREN18 in mouse liver lysate.

Western blot analysis of NUB1 (arrow) using NYREN18 Antibody (N-term) (Cat.APR05044G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NUB1 gene (Lane 2) (Origene Technologies).

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

说明书

数量

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