全部产品分类
品牌 |
Leading Biology | 货号 |
APR04526G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RGS2 Antibody (N-term).
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分子量 |
24382 Da
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细胞定位 |
Antigen Cellular Localization:
Isoform 1: Cell membrane. Cytoplasm. Nucleus, nucleolus Isoform 3: Cell membrane. Cytoplasm. Nucleus, nucleolus
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
4-32 aa
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靶点 |
This RGS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human RGS2.
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亚型 |
Rabbit Ig
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通用名 |
G0S8
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基因ID |
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UniProt ID |
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功能 |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
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总结 |
Regulator of G protein signaling (RGS) family members areregulatory molecules that act as GTPase activating proteins (GAPs)for G alpha subunits of heterotrimeric G proteins. RGS proteins areable to deactivate G protein subunits of the Gi alpha, Go alpha andGq alpha subtypes. They drive G proteins into their inactiveGDP-bound forms. Regulator of G protein signaling 2 belongs to thisfamily. The protein acts as a mediator of myeloid differentiationand may play a role in leukemogenesis.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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