全部产品分类
品牌 |
Leading Biology | 货号 |
APR04509G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SERPINB8 Antibody (C-term).
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分子量 |
42767 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
274-301 aa
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靶点 |
This SERPINB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-301 amino acids from the C-terminal region of human SERPINB8.
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亚型 |
Rabbit Ig
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通用名 |
PI8
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基因ID |
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UniProt ID |
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总结 |
The superfamily of high molecular weight serine proteinaseinhibitors (serpins) regulate a diverse set of intracellular andextracellular processes such as complement activation,fibrinolysis, coagulation, cellular differentiation, tumorsuppression, apoptosis, and cell migration. Serpins arecharacterized by well-conserved a tertiary structure that consistsof 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989[PubMed 2690952]). A critical portion of the molecule, the reactivecenter loop connects beta sheets A and C. Protease inhibitor-8(PI8; SERPINB8) is a member of the ov-serpin subfamily, which,relative to the archetypal serpin PI1 (MIM 107400), ischaracterized by a high degree of homology to chicken ovalbumin,lack of N- and C-terminal extensions, absence of a signal peptide,and a serine rather than an asparagine residue at the penultimateposition (summary by Bartuski et al., 1997 [PubMed9268635]).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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