全部产品分类
品牌 |
Leading Biology | 货号 |
APR04344G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TAPBP Antibody (N-term).
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分子量 |
47626 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
42-70 aa
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靶点 |
This TAPBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human TAPBP.
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亚型 |
Rabbit Ig
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通用名 |
NGS17, TAPA
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基因ID |
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UniProt ID |
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功能 |
Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
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总结 |
This gene encodes a transmembrane glycoprotein whichmediates interaction between newly assembled majorhistocompatibility complex (MHC) class I molecules and thetransporter associated with antigen processing (TAP), which isrequired for the transport of antigenic peptides across theendoplasmic reticulum membrane. This interaction is essential foroptimal peptide loading on the MHC class I molecule. Up to fourcomplexes of MHC class I and this protein may be bound to a singleTAP molecule. This protein contains a C-terminal double-lysinemotif (KKKAE) known to maintain membrane proteins in theendoplasmic reticulum. This gene lies within the majorhistocompatibility complex on chromosome 6. Alternative splicingresults in three transcript variants encoding different isoforms.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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