品牌 |
Leading Biology | 货号 |
APR04282G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MND1 Antibody (C-term).
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分子量 |
23753 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
174-200 aa
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靶点 |
This MND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-200 amino acids from the C-terminal region of human MND1.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity). Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
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总结 |
The product of the MND1 gene associates with HOP2 (MIM608665) to form a stable heterodimeric complex that binds DNA andstimulates the recombinase activity of RAD51 (MIM 179617) and DMC1(MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1and HOP2 genes are indispensable for meioticrecombination.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
MND1 Antibody (C-term) (Cat. APR04282G) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MND1 antibody detected the MND1 protein (arrow). |
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说明书 |
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数量 |
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