全部产品分类
品牌 |
Leading Biology | 货号 |
APR04199G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ASB2 Antibody (N-term).
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分子量 |
65084 Da
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
58-86 aa
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靶点 |
This ASB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human ASB2.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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总结 |
The protein encoded by this gene is a member of theankyrin repeat and SOCS box-containing (ASB) family of proteins.They contain ankyrin repeat sequence and SOCS box domain. The SOCSbox serves to couple suppressor of cytokine signalling (SOCS)proteins and their binding partners with the elongin B and Ccomplex, possibly targeting them for degradation. This gene isinduced by all-trans retinoic acid. In myeloid leukemia cells, theexpression of this encoded protein has been shown to induce growthinhibition and chromatin condensation. Multiple alternativelyspliced transcript variants have been described for this gene buttheir full length sequences are not known.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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