全部产品分类
品牌 |
Leading Biology | 货号 |
APR04189G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FPR1 Antibody (Center).
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分子量 |
38446 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi- pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
165-193 aa
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靶点 |
This FPR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-193 amino acids from the Central region of human FPR1.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520). This response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system (PubMed:1712023, PubMed:10514456).
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总结 |
This gene encodes a G protein-coupled receptor ofmammalian phagocytic cells that is a member of the G-proteincoupled receptor 1 family. The protein mediates the response ofphagocytic cells to invasion of the host by microorganisms and isimportant in host defense and inflammation.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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