全部产品分类
品牌 |
Leading Biology | 货号 |
APR04143G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PLEKHF2 Antibody (Center).
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分子量 |
27798 Da
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细胞定位 |
Antigen Cellular Localization:
Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum. Note=Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots. May translocate to the endoplasmic reticulum in the early phase of apoptosis (PubMed:18288467).
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
71-98 aa
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靶点 |
This PLEKHF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-98 amino acids from the Central region of human PLEKHF2.
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亚型 |
Rabbit Ig
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通用名 |
ZFYVE18
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基因ID |
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UniProt ID |
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功能 |
May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467).
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总结 |
PLEKHF2 (Phafin 2) is a PH and FYVE domain containing protein 2. The FYVE domain and Zinc binding domain targets proteins to membrane lipids via interaction with phosphatidylinositol 3 phosphate, PI3P. The FYVE domain and Zinc binding domain present in Fab1, YOTB, Vac1, and EEA1.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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