品牌 |
Leading Biology | 货号 |
APR04121G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ISG20 Antibody (Center).
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分子量 |
20363 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
29-58 aa
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靶点 |
This ISG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the Central region of human ISG20.
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亚型 |
Rabbit Ig
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通用名 |
HEM45
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基因ID |
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UniProt ID |
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功能 |
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single- stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.
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总结 |
Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. Involved in the antiviral function of IFN against RNA viruses.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
ISG20 Antibody (Center) (Cat. APR04121G) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the ISG20 antibody detected the ISG20 protein (arrow). |
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说明书 |
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数量 |
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