全部产品分类
品牌 |
Leading Biology | 货号 |
APR04091G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MKKS Antibody (C-term).
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分子量 |
62342 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Note=The majority of the protein resides within the pericentriolar material (PCM), a proteinaceous tube surrounding centrioles. During interphase, the protein is confined to the lateral surfaces of the PCM but during mitosis it relocalizes throughout the PCM and is found at the intercellular bridge. The MKSS protein is highly mobile and rapidly shuttles between the cytosol and centrosome
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
408-437 aa
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靶点 |
This MKKS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-437 amino acids from the C-terminal region of human MKKS.
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亚型 |
Rabbit Ig
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通用名 |
BBS6
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基因ID |
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UniProt ID |
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功能 |
Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.
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总结 |
MKKS is a protein with sequence similarity tothe chaperonin family. The encoded protein may have a role inprotein processing in limb, cardiac and reproductive systemdevelopment. Mutations in this gene have been observed in patientswith Bardet-Biedl syndrome type 6 and McKusick-Kaufman syndrome.Two transcript variants encoding the same protein have beenidentified for this gene.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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