全部产品分类
品牌 |
Leading Biology | 货号 |
APR04065G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
|
产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRAF4 Antibody (C-term).
|
||
分子量 |
53543 Da
|
||
细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton
|
||
宿主 |
Rabbit
|
||
种属反应性 |
Human
|
||
免疫原 |
427-455 aa
|
||
靶点 |
This TRAF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 427-455 amino acids from the C-terminal region of human TRAF4.
|
||
亚型 |
Rabbit Ig
|
||
通用名 |
CART1, MLN62, RNF83
|
||
基因ID |
|||
UniProt ID |
|||
功能 |
Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.
|
||
总结 |
This gene encodes a member of the TNF receptor associatedfactor (TRAF) family. TRAF proteins are associated with, andmediate signal transduction from members of the TNF receptorsuperfamily. The encoded protein has been shown to interact withneurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTRinduced cell death and NF-kappa B activation. This protein has beenfound to bind to p47phox, a cytosolic regulatory factor included ina multi-protein complex known as NAD(P)H oxidase. This proteinthus, is thought to be involved in the oxidative activation ofMAPK8/JNK. Alternatively spliced transcript variants have beenobserved but the full-length nature of only one has beendetermined.
|
||
储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
应用 |
WB, E
|
||
稀释方法 |
WB~~1:1000
|
||
图像 |
|
||
说明书 |
|||
数量 |
|
||
| 选择 | 品牌 | 货号 | 产品名称 | 规格 | 分类 | 研究领域 | 说明书 | 数量 | 目录价 | |
| 1 | Leading Biology | APR05963G | EGFR Antibody (Y1092) | 100 μl | Polyclonal Antibodies |
|
￥4950.00 | 订购 询价 | ||
| 2 | Leading Biology | APR03116G | BRCA1 Antibody (aa1847-1863) | 100 μl | Polyclonal Antibodies |
|
￥4950.00 | 订购 询价 | ||
| 3 | Leading Biology | AMM05633G | Bombesin Receptor 2 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 订购 询价 | ||
| 4 | Leading Biology | APR10986G | AP3B1 Antibody (aa2-14) | 50 μg | Polyclonal Antibodies |
|
￥4950.00 | 订购 询价 | ||
| 5 | Leading Biology | APR11512G | Bestrophin-1 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 订购 询价 | ||
| 6 | Leading Biology | APG01407G | A3 Adenosine Receptor Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 订购 询价 |
微信扫描二维码，随时随地与小诺亲密接触，精彩活动，劲爆优惠，触手可得！
销售-华东区