品牌 |
Leading Biology | 货号 |
APR04036G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HYAL1 Antibody (C-term).
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分子量 |
48368 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted. Lysosome
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
280-309 aa
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靶点 |
This HYAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human HYAL1.
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亚型 |
Rabbit Ig
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通用名 |
LUCA1
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基因ID |
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UniProt ID |
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功能 |
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.
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总结 |
This gene encodes a lysosomal hyaluronidase.Hyaluronidases intracellularly degrade hyaluronan, one of the majorglycosaminoglycans of the extracellular matrix. Hyaluronan isthought to be involved in cell proliferation, migration anddifferentiation. This enzyme is active at an acidic pH and is themajor hyaluronidase in plasma. Mutations in this gene areassociated with mucopolysaccharidosis type IX, or hyaluronidasedeficiency. The gene is one of several related genes in a region ofchromosome 3p21.3 associated with tumor suppression. Multipletranscript variants encoding different isoforms have been found forthis gene.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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图像 |
HYAL1 Antibody (C-term) (Cat. APR04036G) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HYAL1 antibody detected the HYAL1 protein (arrow).
HYAL1 Antibody (C-term) (APR04036G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HYAL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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说明书 |
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数量 |
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