全部产品分类
品牌 |
Leading Biology | 货号 |
APR04026G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Mouse Frk Antibody (C-term).
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分子量 |
58844 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.
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宿主 |
Rabbit
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种属反应性 |
Mouse
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免疫原 |
464-491 aa
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靶点 |
This Mouse Frk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-491 amino acids from the C-terminal region of mouse Frk.
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亚型 |
Rabbit Ig
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通用名 |
Bsk, Iyk
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基因ID |
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UniProt ID |
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功能 |
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
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总结 |
Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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