全部产品分类
品牌 |
Leading Biology | 货号 |
APR04020G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GPC3 Antibody (C-term).
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分子量 |
65563 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
465-494 aa
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靶点 |
This GPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human GPC3.
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亚型 |
Rabbit Ig
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通用名 |
OCI5
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基因ID |
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UniProt ID |
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功能 |
Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition.
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总结 |
Cell surface heparan sulfate proteoglycans are composed ofa membrane-associated protein core substituted with a variablenumber of heparan sulfate chains. Members of the glypican-relatedintegral membrane proteoglycan family (GRIPS) contain a coreprotein anchored to the cytoplasmic membrane via a glycosylphosphatidylinositol linkage. These proteins may play a role in thecontrol of cell division and growth regulation. The protein encodedby this gene can bind to and inhibit the dipeptidyl peptidaseactivity of CD26, and it can induce apoptosis in certain celltypes. Deletion mutations in this gene are associated withSimpson-Golabi-Behmel syndrome, also known as Simpson dysmorphiasyndrome. Alternative splicing results in multiple transcriptvariants.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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